The National Pharmacovigilance Centre, Saudi Food and Drug Authority, Riyadh, Saudi Arabia.
Eur J Clin Pharmacol. 2011 May;67(5):527-32. doi: 10.1007/s00228-010-0986-z. Epub 2011 Jan 15.
Approximately 20% of deaths from adverse events are related to medication incidents, costing the NHS an additional £500 million annually. Less than 5% of adverse events are reported. This study aims to assess the reporting rate of medication incidents in NHS facilities in the north east of Scotland, and to describe the types and outcomes of reported incidents among different services. Furthermore, we wished to quantify the proportion of reported incidents according to the reporters' profession.
A retrospective description was made of medication incidents reported to an online reporting system (DATIX) over a 46-month-period (July 2005 to April 2009). Reports originated from acute and community hospitals, mental health, and primary care facilities.
Over the study period there were 2,666 incidents reported with a mean monthly reporting rate of 78.2/month (SD±16.9). 6.1% of all incidents resulted in harm, with insulin being the most commonly implicated medication. Nearly three-quarters (74.2%, n=1,978) of total incidents originated from acute hospitals. Administration incidents were implicated in the majority of the reported medication incidents (59%), followed by prescribing (10.8%) and dispensing (9.9%), while the nondescript "other medication incidents" accounted for 20.3% of total incidents. The majority of reports were made by nursing and midwifery staff (80%), with medical and dental professionals reporting the lowest number of incidents (n=56, 2%).
The majority of medication incidents in this study were reported by nursing and midwifery staff, and were due to administration incidents. There is a clear need to elucidate the reasons for the limited contribution of the medical and dental professionals to reporting medication incidents.
约 20%的不良事件死亡与药物事件有关，使国民保健服务每年额外花费 5 亿英镑。不到 5%的不良事件被报告。本研究旨在评估苏格兰东北部 NHS 设施中药物事件的报告率，并描述不同服务报告事件的类型和结果。此外，我们希望根据报告者的职业来量化报告事件的比例。
对在 46 个月期间（2005 年 7 月至 2009 年 4 月）向在线报告系统（DATIX）报告的药物事件进行回顾性描述。报告来自急症和社区医院、精神卫生和初级保健机构。
在研究期间，共报告了 2666 起事件，平均每月报告率为 78.2/月（SD±16.9）。所有事件中有 6.1%造成了伤害，其中胰岛素是最常涉及的药物。近四分之三（74.2%，n=1978）的总事件来自急症医院。在报告的药物事件中，大多数是给药事件（59%），其次是处方（10.8%）和配药（9.9%），而“其他药物事件”占总事件的 20.3%。大多数报告由护理和助产人员（80%）做出，医疗和牙科专业人员报告的事件最少（n=56，2%）。
本研究中的大多数药物事件由护理和助产人员报告，原因是给药事件。显然需要阐明医学和牙科专业人员对报告药物事件的贡献有限的原因。
