人牙髓中蛋白质p38的免疫细胞化学检测

Immunocytochemical detection of protein p38 in human dental pulp.

作者信息

Casasco A, Calligaro A, Casasco M, Menghini P, Marchetti C, Poggi P, Springall D R, Polak J M

机构信息

Istituto di Istologia ed Embriologia, Università di Pavia, Italy.

出版信息

Arch Oral Biol. 1990;35(8):685-8. doi: 10.1016/0003-9969(90)90038-c.

DOI:10.1016/0003-9969(90)90038-c

PMID:2124102

Abstract

The occurrence and distribution of protein p38 (synaptophysin) were investigated by immunofluorescence. Immunoreactivity for protein p38-like antigen was detected within axons of radicular nerve trunks entering the tooth and within nerve terminals close to blood vessels. Immunoreactive structures were also observed in the para-odontoblastic region. It is proposed that protein p38, translocated within small synaptic vesicles from neuronal perikarya along the axons, may be a reliable marker for detection of nerve endings in human tooth.

摘要

通过免疫荧光法研究了蛋白质p38（突触素）的发生和分布。在进入牙齿的神经根干轴突内以及靠近血管的神经末梢内检测到了p38样抗原的免疫反应性。在成牙本质细胞旁区域也观察到了免疫反应性结构。有人提出，从神经元胞体沿着轴突转运到小突触小泡内的蛋白质p38，可能是检测人类牙齿神经末梢的可靠标志物。