Massey Cancer Center, Virginia Commonwealth University , Richmond, VA 23298-0230, USA.
J Palliat Med. 2011 Mar;14(3):371-3. doi: 10.1089/jpm.2010.0235. Epub 2011 Jan 17.
Abstract Dexmedetomidine (Precedex®) is an alpha-2 adrenergic agonist that can produce sedation and analgesia without causing respiratory depression. Its use has been described in patients undergoing mechanical ventilation, sedation for surgical and nonsurgical procedures, and prevention of withdrawal. We describe its use as an adjuvant analgesic in a patient with cancer pain refractory to multiple treatment modalities.
摘要 右美托咪定（Precedex®）是一种 α-2 肾上腺素能激动剂，可产生镇静和镇痛作用，而不会引起呼吸抑制。它已被用于接受机械通气的患者、手术和非手术程序的镇静以及预防戒断。我们描述了它在一名癌症疼痛患者中的应用，该患者对多种治疗方式均有抵抗。
