School of Nursing Universidad Nacional de Colombia Bogotá, Colombia.
J Adv Nurs. 2011 May;67(5):926-44. doi: 10.1111/j.1365-2648.2010.05568.x. Epub 2011 Jan 18.
To explore the impact of venous leg ulcers on health-related quality of life and analyse the quality of life instruments that have been used for this topic.
Venous leg ulcers represent more than 80% of all chronic leg ulcers. Several studies have demonstrated that health-related quality of life is affected in patients with such lesions.
An integrative review was conducted, together with an additional methodological review of quality of life instruments. Eight electronic databases were searched, and all studies published between 2003 and 2008 were considered in with both qualitative and quantitative approaches and in Spanish, English, French, German and Portuguese. Thus, no restrictions were applied as regards study design.
Twenty-two studies were included; one used mixed methods, three employed qualitative methods and the remaining articles used a quantitative approach. Pain was the factor most frequently identified as affecting health-related quality of life. The generic instruments most commonly used were Short Form-36 and adaptations, the Nottingham Health Profile and EuroQol-5, whilst the disease-specific tools were Hyland, Cardiff Wound Impact Schedule and Charing Cross Venous Leg Ulcer Questionnaire. Two new instruments were also identified, venous leg ulcer quality of life and Sheffield Preference-based Venous Leg Ulcer 5D.
The negative impact of venous leg ulcers on health-related quality of life is confirmed in this review. This impact has been measured using a variety of specific health-related quality of life instruments. However, the review findings suggest that the Charing Cross Venous Leg Ulcer Questionnaire is the most appropriate instrument due to its disease-specific psychometric characteristics.
探讨静脉性腿部溃疡对健康相关生活质量的影响，并分析用于该主题的生活质量工具。
静脉性腿部溃疡占所有慢性腿部溃疡的 80%以上。多项研究表明，此类病变患者的健康相关生活质量受到影响。
进行了综合评价，并对生活质量工具进行了额外的方法学评价。检索了 8 个电子数据库，并考虑了 2003 年至 2008 年之间发表的所有具有定性和定量方法的研究，以及西班牙语、英语、法语、德语和葡萄牙语的研究。因此，对研究设计没有任何限制。
共纳入 22 项研究；一项采用混合方法，三项采用定性方法，其余文章采用定量方法。疼痛是影响健康相关生活质量的最常见因素。最常使用的通用工具是 Short Form-36 和其改编版、Nottingham Health Profile 和 EuroQol-5，而疾病特异性工具是 Hyland、Cardiff Wound Impact Schedule 和 Charing Cross Venous Leg Ulcer Questionnaire。还确定了两种新工具，即静脉性腿部溃疡生活质量和谢菲尔德基于偏好的静脉性腿部溃疡 5D。
本综述证实了静脉性腿部溃疡对健康相关生活质量的负面影响。使用各种特定的健康相关生活质量工具测量了这种影响。然而，综述结果表明，由于 Charing Cross Venous Leg Ulcer Questionnaire 具有特定疾病的心理测量学特征，因此它是最合适的工具。
