Departamento de Microbiología, Universidad de Córdoba, Córdoba, Spain.
FEMS Microbiol Lett. 2011 Apr;317(1):1-8. doi: 10.1111/j.1574-6968.2011.02214.x. Epub 2011 Feb 1.
To maintain optimal intracellular concentrations of alkali-metal-cations, yeast cells use a series of influx and efflux systems. Nonconventional yeast species have at least three different types of efficient transporters that ensure potassium uptake and accumulation in cells. Most of them have Trk uniporters and Hak K(+)-H(+) symporters and a few yeast species also have the rare K(+) (Na(+))-uptake ATPase Acu. To eliminate surplus potassium or toxic sodium cations, various yeast species use highly conserved Nha Na(+) (K(+))/H(+) antiporters and Na(+) (K(+))-efflux Ena ATPases. The potassium-specific yeast Tok1 channel is also highly conserved among various yeast species and its activity is important for the regulation of plasma membrane potential.
为了维持细胞内碱金属阳离子的最佳浓度，酵母细胞使用一系列的输入和输出系统。非传统的酵母物种至少有三种不同类型的高效转运蛋白，可确保钾的摄取和积累在细胞内。它们中的大多数都有 Trk 单载体和 Hak K(+) - H(+)协同转运蛋白，还有一些酵母物种也有罕见的 K(+) (Na(+)) -摄取 ATP 酶 Acu。为了消除多余的钾或有毒的钠离子，各种酵母物种使用高度保守的 Nha Na(+) (K(+)) / H(+)反向转运蛋白和 Na(+) (K(+)) -流出 Ena ATP 酶。钾特异性的酵母 Tok1 通道在各种酵母物种中也高度保守，其活性对质膜电位的调节很重要。
