Postaru Madalina, Tucaliuc Alexandra, Cascaval Dan, Galaction Anca-Irina
Department of Biomedical Science, Faculty of Medical Bioengineering, "Grigore T. Popa" University of Medicine and Pharmacy of Iasi, M. Kogălniceanu 9-13, 700454 Iasi, Romania.
Department of Organic, Biochemical and Food, "Cristofor Simionescu" Faculty of Chemical, Engineering and Environmental Protection, Engineering, "Gheorghe Asachi" Technical University of Iasi, D. Mangeron 73, 700050 Iasi, Romania.
Microorganisms. 2023 Oct 9;11(10):2522. doi: 10.3390/microorganisms11102522.
The importance of yeast cells is known worldwide, as they are the most used microorganisms in biotechnology for bioethanol and biofuel production. Also, they are analyzed and studied for their similar internal biochemical processes to human cells, for a better understanding of cell aging and response to cell stressors. The special ability of cells to develop in both aerobic and anaerobic conditions makes this microorganism a viable model to study the transformations and the way in which cellular metabolism is directed to face the stress conditions due to environmental changes. Thus, this review will emphasize the effects of oxidative, ethanol, and osmotic stress and also the physiological and genetic response of stress mitigation in yeast cells.
酵母细胞的重要性在全球范围内广为人知，因为它们是生物技术中用于生产生物乙醇和生物燃料的最常用微生物。此外，人们对其进行分析和研究，是因为它们的内部生化过程与人类细胞相似，有助于更好地理解细胞衰老和对细胞应激源的反应。细胞在有氧和无氧条件下都能生长的特殊能力，使这种微生物成为研究细胞代谢如何因环境变化而发生转变以及如何应对应激条件的可行模型。因此，本综述将着重阐述氧化应激、乙醇应激和渗透应激的影响，以及酵母细胞缓解应激的生理和遗传反应。
