Department of Plant Pathology and Plant-Microbe Biology, Cornell University, Ithaca, NY 14853, USA.
Fungal Genet Biol. 2011 Apr;48(4):400-7. doi: 10.1016/j.fgb.2011.01.004. Epub 2011 Jan 15.
Three key factors involved in successful plant disease development include the presence of a susceptible host, a virulent pathogen, and a disease-conducive environment. Our understanding of how environmental factors influence disease-conducive or disease-suppressive conditions, and how a pathogen advantageously capitalizes on them, is quite limited. Utilizing the model pathosystem Magnaporthe oryzae-Oryza sativa, we found a significant light-dependent disease suppression. Our genetic data suggest that the blue-light receptor MGWC-1 in M. oryzae is involved in light-dependent disease suppression during the dark-phase (disease-conducive light condition) immediately after pathogen-host contact. Sensing "darkness" is accomplished by MGWC-1, a blue-light receptor in M. oryzae. To explore the potential molecular mechanisms of light-dependent disease suppression we performed a genome-wide microarray experiment and identified several groups of gene families that are differentially regulated during the light-to-dark transition. Our genetic and molecular data provide insights into how a fungal pathogen utilizes ambient light signals for successful disease development.
成功引发植物病害的三个关键因素包括易感宿主、强毒病原体和有利于发病的环境。我们对于环境因素如何影响有利于发病或抑制发病的条件，以及病原体如何有利地利用这些条件，了解非常有限。利用稻瘟病菌-水稻模式体系，我们发现了一种显著的光依赖性病害抑制现象。我们的遗传数据表明，稻瘟病菌中的蓝光受体 MGWC-1 参与了病原菌与宿主接触后立即进入的黑暗期（有利于发病的光条件）中的光依赖性病害抑制。MGWC-1 作为一种蓝光受体，能够感知“黑暗”。为了探究光依赖性病害抑制的潜在分子机制，我们进行了全基因组微阵列实验，鉴定出了在光暗转换过程中差异调控的几组基因家族。我们的遗传和分子数据为了解真菌病原体如何利用环境光信号成功引发病害提供了线索。
