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BZP 派对药丸:苯甲哌嗪作为消遣性药物的研究综述。

BZP-party pills: a review of research on benzylpiperazine as a recreational drug.

机构信息

Department of Sociology, University of Auckland, Human Sciences Building, Room 920, 10 Symonds Street, Private Bag 92019, Auckland 1142, New Zealand.

出版信息

Int J Drug Policy. 2011 Mar;22(2):95-101. doi: 10.1016/j.drugpo.2010.12.002. Epub 2011 Jan 15.

Abstract

BACKGROUND

BZP-party pills are yet another 'designer drug' which mimics the stimulant qualities of amphetamines and MDMA/Ecstasy. As legal markets for the substance have developed in the last decade (especially amongst young people) so has public and governmental concern.

METHODS

This article provides a summary of the available international research on benzylpiperazine (BZP) and its popular use in the compound form known as 'party pills'. Through performing an analysis of the available medical and social scientific literature, the review outlines current knowledge on the compound, the prevalence of usage of BZP-party pills, as well as the associated harms, risks and rationales for use of the drug.

RESULTS

Despite moves towards legislative control of BZP-party pills, the evidence presented suggests limited social and health harms associated with the drug, although research on long term effects is a significant gap in the literature. It also remains inconclusive as to whether BZP-party pills act as a 'gateway' to illegal drugs or, conversely, play a role in harm reduction with illegal drug users turning to legal alternatives; there is some evidence for both positions.

CONCLUSION

With increasing controls of BZP-party pills, and with the increasing numbers of 'legal highs' and new designer drugs on the market, we conclude that new legal alternatives will continue to surface to replace the drug in the future. Considering a harm reduction approach to drug taking, it is suggested that policy makers consider the creation of a legal holding category which restricts and regulates the market in legal highs whilst the social and health harms associated with each drug can be thoroughly investigated.

摘要

背景

BZP-派对药丸是另一种“设计药物”,模仿安非他命和摇头丸/迷幻药的刺激特性。随着过去十年中该物质的合法市场(尤其是在年轻人中)的发展,公众和政府的关注也随之增加。

方法

本文提供了对苯丙哌嗪(BZP)及其在所谓的“派对药丸”复合形式中流行使用的国际研究的总结。通过对现有医学和社会科学文献进行分析,该综述概述了该化合物的现有知识、BZP-派对药丸的使用流行程度,以及与该药物使用相关的危害、风险和合理化理由。

结果

尽管采取了立法控制 BZP-派对药丸的措施,但提出的证据表明,该药物与社会和健康危害相关有限,尽管关于长期影响的研究在文献中存在重大空白。BZP-派对药丸是否作为非法药物的“门户”,或者相反,在非法药物使用者转向合法替代品时起到减少伤害的作用,目前仍尚无定论;这两种观点都有一些证据支持。

结论

随着对 BZP-派对药丸的控制越来越严格,以及市场上越来越多的“合法兴奋剂”和新的设计药物,我们预计未来将继续出现新的合法替代品来替代该药物。考虑到采取减少毒品危害的方法,我们建议政策制定者考虑创建一个合法的持有类别,限制和规范合法兴奋剂市场,同时彻底调查每种药物的社会和健康危害。

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