Digestive Diseases Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran. setoodeh @ ams.ac.ir
Pancreatology. 2010;10(6):702-6. doi: 10.1159/000320695. Epub 2011 Jan 18.
BACKGROUND/AIMS: Endoscopic ultrasonography (EUS) is a useful modality to diagnose causes of pancreatitis. The role of EUS for prediction of pancreatitis severity has not been studied. The aim of this study was to identify the utility of EUS in determining the severity of acute pancreatitis (AP).
All patients diagnosed with pancreatitis consecutively underwent EUS on the 2nd day of their admission. Atlanta criteria were used as the severity index of pancreatitis.
During the study period, 114 patients (74 females, 40 males; mean age of 53.03 ± 17.7 years) were enrolled in the study. The most common cause of AP was gallstone (78.9%). According to the Atlanta criteria, pancreatitis was mild in 72 (63.2%) and severe in 42 (36.8%) patients. In univariate analysis, the presence of peripancreatic edema, pancreas inhomogeneity, common bile duct dilation and ascites were associated with severe pancreatitis. In multivariate analysis, only the presence of peripancreatic edema in EUS correlated with the severity of AP according to the Atlanta criteria (sensitivity, specificity and accuracy: 65.8, 75.7 and 72.2%, respectively).
EUS may be a new useful imaging modality for prediction of severity of AP and may have prognostic significance in the early phase of AP. and IAP.
背景/目的：内镜超声检查（EUS）是诊断胰腺炎病因的一种有用方法。EUS 预测胰腺炎严重程度的作用尚未得到研究。本研究旨在确定 EUS 在确定急性胰腺炎（AP）严重程度中的作用。
所有诊断为胰腺炎的患者均在入院第 2 天行 EUS。亚特兰大标准被用作胰腺炎的严重程度指数。
在研究期间，共有 114 名患者（74 名女性，40 名男性；平均年龄 53.03±17.7 岁）入组。AP 的最常见病因是胆石症（78.9%）。根据亚特兰大标准，胰腺炎轻度 72 例（63.2%），重度 42 例（36.8%）。单因素分析显示，胰周水肿、胰腺不均匀、胆总管扩张和腹水与重症胰腺炎有关。多因素分析显示，EUS 中仅存在胰周水肿与亚特兰大标准的 AP 严重程度相关（敏感性、特异性和准确性分别为 65.8%、75.7%和 72.2%）。
EUS 可能是一种新的有用的影像学方法，可用于预测 AP 的严重程度，并可能在 AP 的早期阶段具有预后意义。
