Obesity and Body Composition Research Center, Zhejiang University School of Public Health, 388 Yu-hang-tang Road, Hangzhou, Zhejiang, 310058, China.
Osteoporos Int. 2011 Dec;22(12):3029-35. doi: 10.1007/s00198-010-1522-9. Epub 2011 Jan 18.
We examined ethnic difference in the association of body fat and trunk fat with bone mineral density (BMD) among Chinese, white, and black subjects. We found that, with greater body and trunk fat, both white and black subjects were more likely to have a low BMD than Chinese subjects.
Ethnic differences in body fat, abdominal fat distribution, and BMD have been found in previous studies between Chinese and white subjects. However, the associations of body fat and abdominal fat distribution with BMD have not been studied, and whether the ethnic differences have an effect on these associations is unclear.
We evaluated 1,147 subjects aged ≥ 18 years (805 Chinese, 193 whites, and 149 blacks). Percent body fat (%BF), percent trunk fat (%TF), and total and regional BMD including that of head, arm, leg, trunk, rib, spine, and pelvis were measured by dual-energy X-ray absorptiometry. Linear regression models were developed to test the association of ethnicity, %BF, and interaction between ethnicity and %BF with BMD. The models were repeated again, replacing %BF with %TF.
Chinese subjects showed lower BMD in total and most regions compared with black and white subjects; however, these differences were eliminated between Chinese and whites within both sexes and between Chinese and black men when age, weight, height, and %BF were added. %BF and %TF were negatively associated with most regional body BMD. The interactions between %BF, %TF, and ethnicity were found in most regional body BMD among Chinese, white, and black subjects for both men and women.
Both %BF and %TF have negative associations with BMD. With greater accumulation of %BF and %TF, both white and black subjects may experience a higher risk of low BMD than Chinese subjects.
研究中国、白种人和黑种人群体脂肪和躯干脂肪与骨密度（BMD）之间的关联是否存在种族差异。
我们评估了 1147 名年龄≥18 岁的受试者（805 名中国人、193 名白人和 149 名黑人）。通过双能 X 射线吸收法测量体脂肪百分比（%BF）、躯干脂肪百分比（%TF）以及总骨密度和各部位骨密度，包括头部、手臂、腿部、躯干、肋骨、脊柱和骨盆。采用线性回归模型来检验种族、%BF 以及种族与%BF 之间的交互作用与 BMD 的相关性。重复这些模型，用 %TF 代替%BF。
与黑人和白人相比，中国人的总体和大多数部位的 BMD 较低；然而，当加入年龄、体重、身高和%BF 后，中国与白人间的男女差异以及中国与黑人间的男性差异均消除。%BF 和 %TF 与大多数部位的体 BMD 呈负相关。在男性和女性中，中国、白种人和黑种人群体的大多数部位的体 BMD 中均发现%BF、%TF 与种族之间存在交互作用。
%BF 和 %TF 均与 BMD 呈负相关。随着%BF 和 %TF 的积累，白人和黑人可能比中国人更容易出现低 BMD。
