Dental School, Department of Paediatric Dentistry, University of Athens, 2 Thivon St., Goudi, 115 27, Athens, Greece.
Lasers Med Sci. 2012 Mar;27(2):313-9. doi: 10.1007/s10103-010-0877-7. Epub 2011 Jan 18.
The purpose of this in vitro investigation was to compare in primary molars, the validity of DIAGNOdent™ 2095 on occlusal caries diagnosis used either separately or in combination with direct and/or indirect visual examinations, based on histological examination as the reference method. In 24 extracted primary molars, 111 occlusal pits were examined for caries by one trained operator (intra-examiner reliability k > 0.80), using the following examination methods: direct visual (DV), indirect visual (IDV), radiographic (XR), and fluorescence (DD) with the DIAGNOdent™. The extent of caries was then determined histologically. Sensitivity, specificity, accuracy, and the area under the ROC curve (AUC) were calculated for each method separately as well as for the combination of DD with DV and/or IDV. The DD accuracy was found both for lesions into enamel and into dentin to be 0.70 while the accuracy of the DD combination with DV and IDV was found to be 0.89. The DD AUC for lesions into enamel and into dentin, 0.68, were not statistically significant different from the other methods (p > 0.5), however the AUC of the combination of DD with DV and IDV, found to be 0.82, was higher than all the other methods, and this was statistically significant for enamel lesions. The validity of DIAGNOdent™ for occlusal caries diagnosis in primary molars was much higher when the DD was used in combination with direct and indirect visual examination, than when used by itself.
本体外研究旨在比较 DIAGNOdent™ 2095 在单独或与直接和/或间接目视检查联合使用时，用于诊断磨牙窝沟龋的有效性，以组织学检查为参考方法。在 24 颗拔除的乳磨牙中，由一位经过培训的操作员（内部检验员可靠性 k > 0.80）使用以下检查方法对 111 个窝沟进行龋病检查：直接目视检查（DV）、间接目视检查（IDV）、放射线照相（XR）和荧光检查（DD）与 DIAGNOdent™ 一起使用。然后根据组织学检查确定龋病的程度。单独计算每种方法的敏感性、特异性、准确性和 ROC 曲线下的面积（AUC），以及 DD 与 DV 和/或 IDV 联合使用的准确性。发现 DD 的准确性在牙釉质和牙本质病变中均为 0.70，而 DD 与 DV 和 IDV 联合使用的准确性为 0.89。DD 在牙釉质和牙本质病变中的 AUC 为 0.68，与其他方法无统计学差异（p > 0.5），但发现 DD 与 DV 和 IDV 联合使用的 AUC 为 0.82，高于所有其他方法，这在牙釉质病变方面具有统计学意义。当 DD 与直接和间接目视检查联合使用时，DIAGNOdent™ 对乳磨牙窝沟龋的诊断有效性明显高于单独使用时。
