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小儿小脑弥漫性间变性少突胶质细胞瘤的临床和放射学特征。

Clinical and radiological features of pediatric cerebellar anaplastic oligodendrogliomas.

机构信息

Department of Neurosurgery, Sri Sathya Sai Institute of Higher Medical Sciences, EPIP Area, Whitefield, Bangalore 560066, India.

出版信息

Indian J Pediatr. 2011 Jul;78(7):880-3. doi: 10.1007/s12098-010-0318-4. Epub 2011 Jan 19.

Abstract

Oligodendrogliomas constitute 4-7% of primary intracranial gliomas in adult and 1% of primary central nervous system tumours in children. The authors report two unusual pediatric cases of anaplastic oligodendroglioma occurring in the cerebellum. The patient with a well-circumscribed lesion with 1p/19q co-deletion had a favorable outcome in comparison with the patient with a diffuse lesion and intact 1p/19q. The discussion elucidates the surgical outcome of such pediatric cerebellar anaplastic oligodendrogliomas in relation to their radiological findings.

摘要

少突胶质细胞瘤占成人原发性颅内胶质瘤的 4-7%,占儿童原发性中枢神经系统肿瘤的 1%。作者报告了 2 例发生在小脑的罕见儿童间变性少突胶质细胞瘤病例。具有 1p/19q 共缺失的边界清楚病变的患者与具有弥漫性病变和完整 1p/19q 的患者相比,预后较好。讨论阐明了此类儿童小脑间变性少突胶质细胞瘤的手术结果与其放射学发现之间的关系。

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