Foo L C
Institute for Medical Research, Kuala Lumpur, Malaysia.
Trop Geogr Med. 1990 Jan;42(1):8-12.
Anthropometric and parasitological data from cross-sectional studies of two groups of primary school children (Group I of Indian origin, 325 boys and 259 girls, age = 7 years; Group II of Malay origin, 284 boys and 335 girls, age = 7-9 years) from two different ecological settings in Peninsular Malaysia were examined for epidemiological evidence of an association between hookworm infection and protein-energy malnutrition. In both ecological groups, significant weight, height and haemoglobin deficits were observed in children with hookworm infection after adjustment for covariables including Ascaris and Trichuris infection intensities and other child and family characteristics. The deficits were related to the intensity of infection based on egg counts. These findings suggest that hookworm may be an important determinant of chronic protein-energy malnutrition, as well as anaemia, in areas where diets are generally inadequate in protein, energy, and iron. Well-controlled intervention studies are needed to confirm these observations.
对来自马来西亚半岛两个不同生态环境的两组小学生（第一组为印度裔，325名男孩和259名女孩，年龄 = 7岁；第二组为马来裔，284名男孩和335名女孩，年龄 = 7 - 9岁）进行横断面研究，检查其人体测量和寄生虫学数据，以寻找钩虫感染与蛋白质 - 能量营养不良之间关联的流行病学证据。在两个生态组中，对包括蛔虫和鞭虫感染强度以及其他儿童和家庭特征等协变量进行调整后，观察到钩虫感染儿童存在显著的体重、身高和血红蛋白不足。这些不足与基于虫卵计数的感染强度有关。这些发现表明，在蛋白质、能量和铁普遍摄入不足的地区，钩虫可能是慢性蛋白质 - 能量营养不良以及贫血的一个重要决定因素。需要进行严格控制的干预研究来证实这些观察结果。
