Wheeler Kevin I, Moore Gregory P, Morley Colin J, Davis Peter G
Newborn Services, Royal Women's Hospital Monash, Melbourne, Victoria, Australia.
J Paediatr Child Health. 2011 Apr;47(4):211-6. doi: 10.1111/j.1440-1754.2010.01946.x. Epub 2011 Jan 18.
The Dräger Babylog 8000plus ventilator (Dräger Medical Systems, Lübeck, Germany) can provide both conventional and high-frequency ventilation (HFV). Dräger recommends specific circuits for each of these modes. We investigated the performance of the Babylog ventilator in HFV mode when used with the recommended circuits for both conventional and HFV.
The Fisher and Paykel RT235 (conventional; Fisher and Paykel Healthcare, Auckland, New Zealand) and Hytrel (HFV; Fisher and Paykel Healthcare) circuits were studied using a 50-mL test lung. Tidal volume, high-frequency minute volume and ventilator alarms were compared at 100 combinations of mean airway pressures (10-16 cm H₂O), frequencies (6-14 Hz) and amplitudes (20-60%).
Tidal volume with the two circuits differed by < 5% for tidal volumes ≤ 2.5 mL. Above this, tidal volumes delivered with the HFV circuit were up to 15% more than that obtained with the conventional ventilation circuit, and high-frequency minute volume differed by up to 30%. With the exception of the highest tidal/minute volumes, the tidal volume delivered using the HFV circuit could also be achieved with adjusted frequency or amplitude when using the conventional circuit. More 'pressure measurement out of range' alarms were noted with the conventional ventilation circuit, particularly at mean airway pressure ≥ 14 cm H₂O and frequency ≤ 10 Hz.
The conventional ventilation circuit may allow delivery of adequate tidal volume for some infants. Where requirements are higher, the HFV circuit allows the Babylog to deliver higher tidal volumes and higher minute volume, and reduce alarms.
德尔格 Babylog 8000plus 呼吸机（德国吕贝克德尔格医疗系统公司）可提供常规通气和高频通气（HFV）。德尔格针对每种模式推荐了特定的回路。我们研究了在 HFV 模式下，当使用推荐的常规通气和 HFV 回路时，Babylog 呼吸机的性能。
使用 50 毫升测试肺对 Fisher 和 Paykel RT235（常规；新西兰奥克兰 Fisher 和 Paykel 医疗保健公司）回路以及 Hytrel（HFV；Fisher 和 Paykel 医疗保健公司）回路进行研究。在 100 种平均气道压力（10 - 16 厘米水柱）、频率（6 - 14 赫兹）和幅度（20 - 60%）的组合下，比较潮气量、高频分钟通气量和呼吸机警报情况。
对于潮气量≤2.5 毫升的情况，两种回路的潮气量差异<5%。在此之上，HFV 回路输送的潮气量比常规通气回路多高达 15%，高频分钟通气量差异高达 30%。除了最高潮气量/分钟通气量外，使用常规回路时，通过调整频率或幅度也可实现 HFV 回路输送的潮气量。常规通气回路出现更多“压力测量超出范围”警报，尤其是在平均气道压力≥14 厘米水柱且频率≤10 赫兹时。
常规通气回路可能为一些婴儿提供足够的潮气量。在需求较高的情况下，HFV 回路可使 Babylog 输送更高的潮气量和更高的分钟通气量，并减少警报。
