Department of Technological Sciences and Development, University of Azores, Sao Miguel, Acores, Portugal.
Nat Prod Res. 2011 Jan;25(2):123-35. doi: 10.1080/14786419.2010.512560.
Water extracts of Hypericum foliosum (HF) from five Azorean Islands were analysed for their antioxidant activity and total phenolic contents. The results were compared with those from medicinal Hypericum species (H. perforatum, H. androsaemum and H. undulatum) and also with Azorean green tea. HF exhibited strong scavenging activity (87-91%) and moderate inhibition of linoleic acid oxidation (56-72%), and presented no significant difference to the other studied plants; in contrast, the synthetic antioxidant butylated hydroxyltoluene showed antioxidant activity values of 22% and 88%, respectively. The average value of phenolics in HF was higher than that in the other Hypericum species and lower than that in tea. Additionally, the phenolic profiles of the Hypericum species were compared by reverse phase-high performance liquid chromatography/ultraviolet (RP-HPLC/UV). The method presented permits the simultaneous determination of phenolic acids, flavonoids, hypericin and hyperforin within 55 min. The most similar profile was observed between HF and H. androsaemum. This study indicates that HF is a source of bioactive compounds with potential health benefits.
从亚速尔群岛的五个岛屿中提取贯叶金丝桃（HF）的水提取物，分析其抗氧化活性和总酚含量。将结果与药用贯叶金丝桃（H. perforatum、H. androsaemum 和 H. undulatum）和亚速尔绿茶进行了比较。HF 表现出很强的清除活性（87-91%）和适度的抑制亚油酸氧化（56-72%），与其他研究植物没有显著差异；相比之下，合成抗氧化剂丁基羟基甲苯的抗氧化活性值分别为 22%和 88%。HF 中的平均酚含量高于其他贯叶金丝桃物种，低于茶。此外，通过反相高效液相色谱/紫外（RP-HPLC/UV）比较了贯叶金丝桃物种的酚类图谱。该方法允许在 55 分钟内同时测定酚酸、类黄酮、金丝桃素和金丝桃苷。HF 和 H. androsaemum 之间观察到最相似的图谱。这项研究表明，HF 是具有潜在健康益处的生物活性化合物的来源。
