Department of Nuclear Medicine, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.
Contrast Media Mol Imaging. 2011 Jul-Aug;6(4):169-77. doi: 10.1002/cmmi.428. Epub 2011 Jan 19.
Optical imaging essentially refers to in vivo fluorescence imaging and bioluminescence imaging. These types of imaging are widely used visualization methods in biomedical research and are important in molecular imaging. A new generation of imaging agents called multimodal probes have emerged in the past few years. These probes can be detected by two or more imaging modalities, which harnesses the strengths of the different modalities and enables researchers to obtain more information than can be achieved using only one modality. Owing to its low cost and the large number of probes available, the optical method plays an important role in multimodality imaging. In this mini-review, we describe the available multimodal imaging probes for in vivo imaging that combine optical imaging with other modalities.
光学成像是指体内荧光成像和生物发光成像。这些类型的成像是生物医学研究中广泛使用的可视化方法，在分子成像中也很重要。在过去几年中，出现了新一代的成像剂，称为多模态探针。这些探针可以通过两种或更多种成像模式进行检测，利用不同模式的优势，使研究人员能够获得比仅使用一种模式更多的信息。由于其成本低，并且有大量的探针可供选择，因此光学方法在多模态成像中起着重要作用。在这篇综述中，我们描述了将光学成像与其他模式相结合的体内成像用多模态成像探针。
