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抗精神病药恶性综合征:综述

Neuroleptic malignant syndrome: a review.

作者信息

O'Brien R A, Young G B

出版信息

Can Fam Physician. 1989 May;35:1119-22.

Abstract

There has recently been interest in neuroleptic malignant syndrome (NMS) as the disorder has been better characterized. Nms is still poorly recognized, however, by most physicians. Hyperpyrexia, rigidity, altered consciousness, autonomic instability, and enzymatic evidence of muscle breakdown after drug intake are the cardinal features. The authors of this article review the proposed pathogenesis, complications, and treatment of NMS.

摘要

近年来,随着对神经阻滞剂恶性综合征(NMS)的特征有了更深入的了解,人们对它产生了兴趣。然而,大多数医生对NMS的认识仍然不足。高热、强直、意识改变、自主神经功能不稳定以及服药后肌肉分解的酶学证据是其主要特征。本文作者回顾了NMS的发病机制、并发症及治疗方法。

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本文引用的文献

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Neuroleptic malignant syndrome: response to dantrolene sodium.
Ann Intern Med. 1983 Feb;98(2):183-4. doi: 10.7326/0003-4819-98-2-183.
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Neuroleptic malignant syndrome: successful treatment with dantrolene and bromocriptine.
Ann Neurol. 1983 Jul;14(1):89-90. doi: 10.1002/ana.410140117.
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Neuroleptic malignant syndrome.
J Emerg Med. 1984;1(3):207-11. doi: 10.1016/0736-4679(84)90073-8.

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