Fielding S, Szewczak M R
J Clin Psychiatry. 1984 Apr;45(4 Pt 2):12-20.
Nomifensine has demonstrated efficacy in several animal models that have been found to be predictive of clinical antidepressant activity, and has also been found to have a low potential for both cardiovascular and anticholinergic side effects. A comparison of nomifensine's profile with those of standard antidepressant agents shows this drug to possess clear advantages which may make it an attractive choice for the treatment of endogenous depression.
诺米芬辛在多种动物模型中已显示出疗效，这些模型已被发现可预测临床抗抑郁活性，并且还发现它具有较低的心血管和抗胆碱能副作用风险。将诺米芬辛的特性与标准抗抑郁药的特性进行比较表明，这种药物具有明显优势，这可能使其成为治疗内源性抑郁症的一个有吸引力的选择。
