Boshkov L K, Kelton J G
Can Fam Physician. 1988 Nov;34:2521-365.
Since the 1950s, intramuscular gammaglobulin preparations have been used for antibody replacement in patients with immune deficiency syndromes. The authors of this article discuss newer intravenous formulations which have expanded the role of IgG preparations from simple antibody replacement to therapeutic use in high doses as an immune suppressant and an autoimmune modulator.
自20世纪50年代以来,肌肉注射用丙种球蛋白制剂一直用于免疫缺陷综合征患者的抗体替代治疗。本文作者讨论了更新的静脉注射制剂,这些制剂扩大了IgG制剂的作用,从单纯的抗体替代扩展到高剂量作为免疫抑制剂和自身免疫调节剂的治疗用途。