Nakamura Tomohiro, Ogita Manabu, Ako Junya, Momomura Shin-Ichi
Cardiovascular Division, Saitama Citizens Medical Center, 299-1 Shimane, Nishi-ku, Saitama 331-0054, Japan.
Int J Vasc Med. 2010;2010:134692. doi: 10.1155/2010/134692. Epub 2011 Jan 4.
The purpose of this study was to evaluate the relation between gender and plaque characteristics assessed by virtual histology-intravascular ultrasound (VH-IVUS) in patients with stable angina pectoris. Preinterventional VH-IVUS image was available for analysis in 88 men and 60 women patients. Women had significantly smaller vessel volume (12.7 ± 3.9 versus 14.5 ± 4.2 mm(3)/mm, P = .01) and smaller plaque volume (8.4 ± 3.5 versus 9.7 ± 3.5 mm(3)/mm, P = .04). However, these differences were no longer significant when corrected for body surface area (BSA). In VH-IVUS analysis, women had significantly higher dense calcium when corrected for BSA in the culprit lesion (volume: 0.32 ± 0.26 versus 0.44 ± 0.40 mm(3)/mm/BSA, P = .03; proportion: 8.2 ± 6.1 versus 11.2 ± 7.6%, P = .009). VH-IVUS analysis of plaque components in elderly patients with stable angina showed that women had higher calcium contents compared with men.
本研究的目的是评估在稳定型心绞痛患者中，性别与通过虚拟组织学血管内超声（VH-IVUS）评估的斑块特征之间的关系。88例男性和60例女性患者有介入前VH-IVUS图像可供分析。女性的血管容积明显较小（12.7±3.9对14.5±4.2 mm(3)/mm，P = .01），斑块容积也较小（8.4±3.5对9.7±3.5 mm(3)/mm，P = .04）。然而，在校正体表面积（BSA）后，这些差异不再显著。在VH-IVUS分析中，在校正罪犯病变的BSA后，女性的致密钙含量明显更高（容积：0.32±0.26对0.44±0.40 mm(3)/mm/BSA，P = .03；比例：8.2±6.1对11.2±7.6%，P = .009）。对老年稳定型心绞痛患者斑块成分的VH-IVUS分析显示，女性的钙含量高于男性。
