[强直性脊柱炎患者使用阿达木单抗治疗期间发生急性弓形虫感染：一例报告]
[Acute toxoplasmosis infection in a patient with ankylosing spondylitis treated with adalimumab: a case report].
作者信息
Azevedo V F, Pietrovski C F, de Almeida Santos M
机构信息
Hospital de Clínicas, Federal University of Paraná, Brazil.
出版信息
Reumatismo. 2010 Oct-Dec;62(4):283-5. doi: 10.4081/reumatismo.2010.283.
PMID:21253622
Abstract
We present a case of acute toxoplasmosis infection in a 36-year-old man with long-standing ankylosing spondylitis, treated with adalimumab. We review the association between antitumor necrosis factor therapy and toxoplasmosis. Our case illustrates that opportunistic infections may occur in patients treated with adalimumab, and emphasizes the importance of clinical suspicion and serological tests.
摘要
我们报告了一例36岁患有长期强直性脊柱炎且正在接受阿达木单抗治疗的男性急性弓形虫感染病例。我们回顾了抗肿瘤坏死因子治疗与弓形虫病之间的关联。我们的病例表明，接受阿达木单抗治疗的患者可能会发生机会性感染，并强调了临床怀疑和血清学检测的重要性。
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