Pieh-Beisse C, Lagrèze W A
Universitäts-Augenklinik Freiburg, Killianstr. 5, 79106 Freiburg, Deutschland.
Ophthalmologe. 2011 Feb;108(2):178-82. doi: 10.1007/s00347-010-2324-3.
Nystagmus can be associated with strong discomfort due to oscillopsia, blurry vision and dizziness. Since generally no curative treatment methods exist, studies focus on potential pharmaceuticals to dampen the nystagmus. An overview is given on which forms of nystagmus can be treated with what kind of pharmacological substances and their possible mechanism of nystagmus dampening. Controlled studies found gabapentin and memantine to be effective in acquired pendular nystagmus and early-onset idiopathic nystagmus, and an efficacy of 4-aminopyridine in downbeat nystagmus.
眼球震颤可能会因视振荡、视力模糊和头晕而导致强烈不适。由于一般不存在治愈性治疗方法，研究集中在抑制眼球震颤的潜在药物上。本文综述了哪些类型的眼球震颤可用何种药理物质治疗及其抑制眼球震颤的可能机制。对照研究发现加巴喷丁和美金刚对获得性钟摆型眼球震颤和早发性特发性眼球震颤有效，4-氨基吡啶对下跳性眼球震颤有效。
