Department of Neurology, Antwerp University Hospital, Wilrijkstraat 10, Antwerp B2650, Belgium.
Muscle Nerve. 2011 Feb;43(2):168-70. doi: 10.1002/mus.21853.
Stimulated single-fiber electromyography (SSFEMG) is a valuable diagnostic tool in cases of myasthenia gravis with limited disease. From 1990 to 2008 SSFEMG in the orbicularis oculi muscle (OO) was performed in a cohort of 456 patients referred with clinical suspicion of myasthenia gravis (MG) and exclusively ocular symptoms. A diagnosis of MG was made on clinical grounds in 103 patients. In this patient cohort, the specificity of SSFEMG for myasthenia was 97%, and the sensitivity was 80%. MG patients with a normal SSFEMG had a benign clinical course. This study confirms a high specificity and sensitivity of SSFEMG when it is performed on patients suspected to have ocular MG. In such patients, a normal SSFEMG of the OO predicts a benign clinical course.
眼轮匝肌的单纤维肌电图（SSFEMG）在局限性重症肌无力（MG）的诊断中具有重要价值。1990 年至 2008 年间，我们对 456 例因临床怀疑 MG 且仅有眼肌症状而就诊的患者进行了眼轮匝肌 SSFEMG 检查。其中 103 例患者根据临床标准诊断为 MG。在该患者队列中，SSFEMG 对 MG 的特异性为 97%，敏感性为 80%。SSFEMG 正常的 MG 患者具有良性临床过程。本研究证实，当对疑似眼肌型 MG 的患者进行 SSFEMG 检查时，其特异性和敏感性均较高。在这些患者中，眼轮匝肌 SSFEMG 正常可预测良性临床过程。
