Rivero A, Crovetto L, Lopez L, Maselli R, Nogués M
Raúl Carrea Institute of Neurological Research, Buenos Aires, Argentina.
Muscle Nerve. 1995 Sep;18(9):943-7. doi: 10.1002/mus.880180904.
We performed single fiber electromyography (SFEMG) in the superior rectus and levator palpebralis (SR-LP) muscles of 17 patients with pure ocular myasthenia gravis (MG) and 9 controls. Thirteen patients were also assessed with SFEMG in the orbicularis oculi (OO) muscle. All the MG patients but none of the control subjects showed abnormal SFEMG jitter in the SR-LP muscles. On the other hand, only 62% of the MG patients had abnormal SFEMG jitter in the OO muscle. The procedure was well tolerated by the patients, and complications were minor. We conclude that SFEMG of the SR-LP muscles is a safe and highly sensitive technique for the diagnosis of ocular MG.
我们对17例单纯眼肌型重症肌无力（MG）患者和9名对照者的上直肌和提上睑肌（SR-LP）进行了单纤维肌电图（SFEMG）检查。还对13例患者的眼轮匝肌（OO）进行了SFEMG评估。所有MG患者的SR-LP肌肉均显示SFEMG颤抖异常，而对照者均未出现异常。另一方面，仅62%的MG患者的OO肌肉存在SFEMG颤抖异常。患者对该检查耐受性良好，并发症轻微。我们得出结论，SR-LP肌肉的SFEMG是诊断眼肌型MG的一种安全且高度敏感的技术。
