Filaretova L P
Ross Fiziol Zh Im I M Sechenova. 2010 Sep;96(9):924-35.
The review focuses on the concept of biological stress pioneered by Hans Selye, who demonstrated a key involvement of the pituitary-adrenocortical axis in the response to stress. It discusses the historic background of development of the stress concept and some aspects of modern physiological researches related to stress-induced activation of the hypothalamic-pituitary-adrenocortical axis. We focus mainly on the results demonstrating that stress-induced activation of the hypothalamic-pituitary-adrenocortical axis is a gastroprotective component of stress response.
这篇综述聚焦于汉斯·塞尔耶开创的生物应激概念,他证明了垂体 - 肾上腺皮质轴在应激反应中的关键作用。文中讨论了应激概念发展的历史背景以及与应激诱导的下丘脑 - 垂体 - 肾上腺皮质轴激活相关的现代生理学研究的一些方面。我们主要关注的结果表明,应激诱导的下丘脑 - 垂体 - 肾上腺皮质轴激活是应激反应的胃保护成分。