Maxová H, Vasilková M, Tkaczyk J, Vízek M
Ustav patologické fyziologie, 2. LF UK, Praha.
Cesk Fysiol. 2010;59(1):21-3.
Disodium cromoglycate (DSCG) is a compound commonly used in the treatment of allergic diseases. The effect of DSCG is due to its ability to stabilize the mast cell membrane and to prevent release of histamine and inflammatory mediators. Mast cells are also an abundant source of tissue metalloproteinases, serine proteases and growth factors, which play an important role in the processes of the tissue remodeling. In this view the DSCG is a substance which allows us to study the mechanisms of the pulmonary vascular bed remodeling in the experimental animals exposed to chronic hypoxia and in a phase of the recovery from hypoxia.
色甘酸钠（DSCG）是一种常用于治疗过敏性疾病的化合物。DSCG的作用是由于其能够稳定肥大细胞膜并防止组胺和炎症介质的释放。肥大细胞也是组织金属蛋白酶、丝氨酸蛋白酶和生长因子的丰富来源，这些在组织重塑过程中起重要作用。从这个角度来看，DSCG是一种能让我们研究暴露于慢性缺氧及缺氧恢复期的实验动物肺血管床重塑机制的物质。
