School of Life Sciences, John Muir Building, Heriot-Watt University, Riccarton, Edinburgh EH14 4AS, Scotland, UK.
Fish Shellfish Immunol. 2011 Mar;30(3):845-50. doi: 10.1016/j.fsi.2011.01.008. Epub 2011 Jan 19.
The development and duration of immune protection against Aeromonas hydrophila infections with garlic as an immunostimulant in rainbow trout Oncorhynchus mykiss was studied. Rainbow trout fingerlings of 14 g average weight were fed with 0 g (=Control), 0.5 g and 1.0 g of garlic 100 g(-1) of feed for 14 days. Physiological factors, biochemical, immunological, haematological parameters and electrolyte indices were evaluated after a further 14, 21 and 28 days before challenge with Aeromonas hydrophila. Fourteen days after the cessation of feeding with garlic, mortality rates of 12% (relative percent survival [RPS] = 86%) and 16% (RPS = 80%) were recorded in groups which received 0.5 g and 1.0 g of garlic 100 g(-1) of feed, respectively, compared to 84% mortalities in the controls. The corresponding RPS 21 days after ending the feeding regime was 75% and 68, respectively. One week later, the RPS had dropped to 55% and 46% in the groups fed with 0.5 g and 1.0 g garlic 100 g(-1) of feed, respectively.
研究了大蒜作为免疫增强剂对虹鳟鱼（Oncorhynchus mykiss）抗嗜水气单胞菌感染的免疫保护的发展和持续时间。平均重量为 14 克的虹鳟鱼苗用 0 克（=对照）、0.5 克和 1.0 克大蒜 100 克（-1）饲料喂养 14 天。在受到嗜水气单胞菌攻击前，进一步评估了 14、21 和 28 天后的生理因素、生化、免疫、血液学参数和电解质指数。停止用大蒜喂养 14 天后，分别接受 0.5 克和 1.0 克大蒜 100 克（-1）饲料的组的死亡率为 12%（相对生存百分比[RPS] = 86%）和 16%（RPS = 80%），而对照组的死亡率为 84%。停止喂养后 21 天，相应的 RPS 分别为 75%和 68%。一周后，分别用 0.5 克和 1.0 克大蒜 100 克（-1）饲料喂养的组的 RPS 下降到 55%和 46%。
