一项关于水杨酸铋治疗幽门螺杆菌相关性胃炎的安慰剂对照试验。
A placebo controlled trial of bismuth salicylate in Helicobacter pylori associated gastritis.
作者信息
Kazi J I, Jafarey N A, Alam S M, Zuberi S J, Kazi A M, Qureshi H, Ahmed W
机构信息
Department of Pathology, Pakistan Medical Research Council, Karachi.
出版信息
J Pak Med Assoc. 1990 Jul;40(7):154-6.
In a placebo controlled prospective clinical trial of bismuth salicylate in helicobacter pylori associated gastritis, 52 adult patients were randomly allocated to treatment with bismuth salicylate or placebo. Helicobacter pylori were totally cleared in 77% patients in bismuth group but none in placebo group (P less than 0.001). Resolution of gastritis (P less than 0.001) and improvement of symptoms (P less than 0.01) were significantly better in patients where H. pylori infection cleared as compared to patients where the infection persisted.
在一项关于水杨酸铋治疗幽门螺杆菌相关性胃炎的安慰剂对照前瞻性临床试验中，52名成年患者被随机分配接受水杨酸铋或安慰剂治疗。铋剂组77%的患者幽门螺杆菌被完全清除，而安慰剂组无一例清除（P<0.001）。与感染持续的患者相比，幽门螺杆菌感染清除的患者胃炎缓解情况（P<0.001）和症状改善情况（P<0.01）明显更好。
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