Dam M
University Clinic of Neurology, Hvidovre Hospital, Denmark.
Epilepsia. 1990;31 Suppl 4:S26-9. doi: 10.1111/j.1528-1157.1990.tb05866.x.
Overall, children with epilepsy have poorer concentration and mental processing and are less alert than age-matched controls. The relationship between cognitive functioning and epilepsy is complex, however, with widely differing degrees of intellectual impairment--ranging from minimal to severe and progressive--related to diverse types of epileptic seizures, syndromes, and etiological factors. Prolonged and frequently repeated seizures are typically associated with more severe effects on cognitive functioning, particularly if epilepsy is symptomatic, i.e., secondary to a demonstrable brain lesion. A combination of such factors may contribute to the mental deterioration seen in many children suffering from severe epilepsy.
总体而言，癫痫患儿的注意力和心理加工能力较差，且不如年龄匹配的对照组警觉。然而，认知功能与癫痫之间的关系很复杂，不同类型的癫痫发作、综合征和病因导致了广泛不同程度的智力损害，从轻微到严重且呈进行性发展。长时间且频繁发作的癫痫通常对认知功能有更严重的影响，特别是当癫痫是症状性的，即继发于可证实的脑损伤时。这些因素的综合作用可能导致许多重度癫痫患儿出现智力衰退。
