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体外膜肺氧合(ECMO)在危重症成年患者中的应用的基本原则和证据基础综述。

A review of the fundamental principles and evidence base in the use of extracorporeal membrane oxygenation (ECMO) in critically ill adult patients.

机构信息

Department of Surgery, Division of Traumatology and Surgical Critical Care, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.

出版信息

J Intensive Care Med. 2011 Jan-Feb;26(1):13-26. doi: 10.1177/0885066610384061.

DOI:10.1177/0885066610384061
PMID:21262750
Abstract

Extracorporeal membrane oxygenation (ECMO) comprises a commonly used method of extracorporeal life support. It has proven efficacy and is an accepted modality of care for isolated respiratory or cardiopulmonary failure in neonatal and pediatric populations. In adults, there are conflicting studies regarding its benefit, but it is possible that ECMO may be beneficial in certain adult populations beyond postcardiotomy heart failure. As such, all intensivists should be familiar with the evidence-base and principles of ECMO in adult population. The purpose of this article is to review the evidence and to describe the fundamental steps in initiating, adjusting, troubleshooting, and terminating ECMO so as to familiarize the intensivist with this modality.

摘要

体外膜肺氧合(ECMO)是一种常用的体外生命支持方法。它已被证明具有疗效,是新生儿和儿科人群孤立性呼吸或心肺衰竭的一种公认的治疗方式。在成人中,关于其益处的研究存在争议,但 ECMO 可能对某些成人人群有益,而不仅仅是心脏手术后心力衰竭的患者。因此,所有重症监护医生都应该熟悉 ECMO 在成人中的证据基础和原则。本文的目的是回顾相关证据,并描述启动、调整、解决问题和终止 ECMO 的基本步骤,以使重症监护医生熟悉这一治疗方式。

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