Can Fam Physician. 1987 Feb;33:385-8.
Hyposensitization therapy is useful in the treatment of allergic disease causing rhinoconjunctivitis and asthma, and in the prophylaxis against anaphylaxis to hymenoptera stings. It may be of value in some patients with drug sensitivities. Its effectiveness has been proven by objective clinical studies, and the immune mechanisms responsible for patients' response have been demonstrated in vivo and in vitro. A prerequisite for effectiveness is the identification of the offending antigen and the availability of that antigen in a standardized, purified, stable extract. Modified antigens with special immunologic properties show much promise for the future.
脱敏疗法对治疗引起鼻结膜炎和哮喘的过敏性疾病以及预防蜂类螫刺引起的过敏反应很有用。它对某些药物过敏的患者可能有价值。其有效性已通过客观的临床研究证明,并且体内和体外都已证明了导致患者反应的免疫机制。有效性的前提是识别致病抗原,以及提供标准化、纯化、稳定的提取物中的该抗原。具有特殊免疫特性的改良抗原具有广阔的应用前景。