脱敏治疗。
Hyposensitization therapy.
出版信息
Can Fam Physician. 1987 Feb;33:385-8.
Abstract
Hyposensitization therapy is useful in the treatment of allergic disease causing rhinoconjunctivitis and asthma, and in the prophylaxis against anaphylaxis to hymenoptera stings. It may be of value in some patients with drug sensitivities. Its effectiveness has been proven by objective clinical studies, and the immune mechanisms responsible for patients' response have been demonstrated in vivo and in vitro. A prerequisite for effectiveness is the identification of the offending antigen and the availability of that antigen in a standardized, purified, stable extract. Modified antigens with special immunologic properties show much promise for the future.
摘要
脱敏疗法对治疗引起鼻结膜炎和哮喘的过敏性疾病以及预防蜂类螫刺引起的过敏反应很有用。它对某些药物过敏的患者可能有价值。其有效性已通过客观的临床研究证明，并且体内和体外都已证明了导致患者反应的免疫机制。有效性的前提是识别致病抗原，以及提供标准化、纯化、稳定的提取物中的该抗原。具有特殊免疫特性的改良抗原具有广阔的应用前景。
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本文引用的文献
1
Clinical relevance of the venom-specific immunoglobulin G antibody level during immunotherapy.免疫治疗期间毒液特异性免疫球蛋白G抗体水平的临床相关性。
J Allergy Clin Immunol. 1982 Jun;69(6):489-93. doi: 10.1016/0091-6749(82)90172-5.
2
Aspirin desensitization in aspirin-sensitive asthmatic patients: clinical manifestations and characterization of the refractory period.阿司匹林敏感型哮喘患者的阿司匹林脱敏：临床表现及不应期特征
J Allergy Clin Immunol. 1982 Jan;69(1 Pt 1):11-9. doi: 10.1016/0091-6749(82)90081-1.
3
A controlled study of the effectiveness of the Rinkel method of immunotherapy for ragweed pollen hay fever.一项关于林克尔免疫疗法治疗豚草花粉性枯草热有效性的对照研究。
J Allergy Clin Immunol. 1980 Apr;65(4):288-97. doi: 10.1016/0091-6749(80)90158-x.
4
Effect of immunotherapy on immunoglobulin E and immunoglobulin G antibodies to ragweed antigens: a six-year prospective study.免疫疗法对豚草抗原免疫球蛋白E和免疫球蛋白G抗体的影响：一项为期六年的前瞻性研究。
J Allergy Clin Immunol. 1982 Oct;70(4):261-71. doi: 10.1016/0091-6749(82)90062-8.
5
Local nasal immunotherapy for ragweed-allergic rhinitis. III. A second year of treatment.豚草过敏性鼻炎的局部鼻内免疫疗法。III. 治疗的第二年。
Clin Allergy. 1983 Nov;13(6):509-19. doi: 10.1111/j.1365-2222.1983.tb02632.x.
6
Asthma and increases in nonallergic bronchial responsiveness from seasonal pollen exposure.
J Allergy Clin Immunol. 1983 Apr;71(4):399-406. doi: 10.1016/0091-6749(83)90069-6.
7
Tissue mast cells in immediate hypersensitivity.
Hosp Pract (Off Ed). 1982 Nov;17(11):98-108. doi: 10.1080/21548331.1982.11702416.
8
Immunotherapy in cat-induced asthma. Double-blind trial with evaluation of in vivo and in vitro responses.
J Allergy Clin Immunol. 1984 Sep;74(3 Pt 1):230-9. doi: 10.1016/0091-6749(84)90251-3.
9
Controlled evaluation of allergoid in the immunotherapy of ragweed hay fever.变应原样物质用于豚草花粉热免疫治疗的对照评估
J Allergy Clin Immunol. 1982 Oct;70(4):248-60. doi: 10.1016/0091-6749(82)90061-6.
10
Antigen-specific desensitization of patients allergic to penicillin.
J Allergy Clin Immunol. 1982 Jun;69(6):500-8. doi: 10.1016/0091-6749(82)90174-9.
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