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深入探讨 HIV 抗体检测:1. 它们的准确性如何?

A Critical Look at HIV-Antibody Tests: 1. How Accurate Are They?

出版信息

Can Fam Physician. 1987 Sep;33:2005-11.

Abstract

As the AIDS epidemic spreads, many patients are asking their primary-care physicians to perform AIDS (HIV-antibody) testing, and in some settings, clinical circumstances prompt physicians to consider ordering the test. As a result, thousands of HIV-antibody tests are being requested each month by Canadian family doctors, where none were available only two years ago. Yet particular characteristics of HIV infection make these tests very unlike most blood tests, since their use carries clear risks as well as benefits. The authors review these risks and benefits in two sequential articles. In this first paper, they review the quantitative aspects of test accuracy (validity). In a sequential paper, to be published in next month's issue, they will discuss the risks and benefits of performing the test in various clinical circumstances.

摘要

随着艾滋病疫情的蔓延,许多患者要求他们的初级保健医生进行艾滋病(HIV 抗体)检测,在某些情况下,临床情况促使医生考虑开这种检测。结果,加拿大家庭医生每月要求进行数千次 HIV 抗体检测,而就在两年前,还根本无法进行这种检测。然而,HIV 感染的特殊特征使得这些检测与大多数血液检测非常不同,因为这些检测的使用既有明确的风险,也有好处。作者在两篇连续的文章中对这些风险和好处进行了回顾。在第一篇文章中,他们回顾了检测准确性(有效性)的定量方面。在下个月的下期,他们将在另一篇连续文章中讨论在各种临床情况下进行检测的风险和好处。

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本文引用的文献

9
Screening for HIV: can we afford the false positive rate?HIV筛查:我们能否承受假阳性率?
N Engl J Med. 1987 Jul 23;317(4):238-41. doi: 10.1056/NEJM198707233170410.

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