Department of Clinical Medicine, Trinity Centre, The Adelaide and Meath Hospital, Trinity College Dublin, Tallaght, Dublin 24, Ireland.
Ir J Med Sci. 2011 Jun;180(2):549-52. doi: 10.1007/s11845-010-0650-8. Epub 2011 Jan 25.
In Ireland, colorectal cancer (CRC) is the second most frequently diagnosed cancer in men, after prostate cancer, and the second most frequently diagnosed cancer in women, after breast cancer. By 2020, the number of new cases diagnosed annually in Ireland is projected to have increased by 79% in men and 56% in women. Organised screening for CRC is already underway or is in the process of being rolled out in several European countries, either at a regional or national level. The Adelaide and Meath Hospital/ Trinity College Dublin Colorectal Cancer Screening Programme (TTC-CRC-SP) is Ireland's first pilot population based bowel screening programme.
Based on a biennial test model the pilot aimed to assess the accuracy of FIT and to evaluate the whole programme based on established international key performance indices.
To date 9,993 individuals aged 50-74 years have been invited to participate in the TTC-CRC-SP with over 5,000 FIT's analysed. Overall uptake was 51% and FIT positivity was 10%. The programme has undertaken over 400 screening colonoscopies and detected 154 precancerous adenomas and 38 cancerous lesions.
The first round of The Adelaide and Meath Hospital Tallaght/Trinity College Dublin Colorectal Cancer Screening Programme has been highly successful and confirmed that there is an advantage for FIT based two stage bowel cancer screening programmes.
在爱尔兰,结直肠癌(CRC)是男性中仅次于前列腺癌的第二大常见癌症,在女性中仅次于乳腺癌。到 2020 年,预计爱尔兰每年新诊断的病例数量将在男性中增加 79%,在女性中增加 56%。在几个欧洲国家,已经或正在开展针对 CRC 的有组织筛查,范围涉及地区或全国。阿德莱德和梅多斯医院/都柏林三一学院结直肠癌筛查计划(TTC-CRC-SP)是爱尔兰首个基于人群的试点肠道筛查计划。
基于两年一次的测试模型,该试点旨在评估 FIT 的准确性,并根据既定的国际关键绩效指标评估整个计划。
迄今为止,已有 9993 名 50-74 岁的个体受邀参加 TTC-CRC-SP,已有超过 5000 个 FIT 进行了分析。总体参与率为 51%,FIT 阳性率为 10%。该计划已经进行了超过 400 次筛查结肠镜检查,发现了 154 个癌前腺瘤和 38 个癌性病变。
第一轮阿德莱德和梅多斯医院塔拉赫特/都柏林三一学院结直肠癌筛查计划非常成功,并证实基于 FIT 的两阶段结直肠癌筛查计划具有优势。