Medical and Biological Sciences Building, University of St Andrews, North Haugh, St Andrews, Fife KY16 9TF, UK.
Biochem Soc Trans. 2011 Jan;39(1):163-8. doi: 10.1042/BST0390163.
Most of the core components of the archaeal chromosomal DNA replication apparatus share significant protein sequence similarity with eukaryotic replication factors, making the Archaea an excellent model system for understanding the biology of chromosome replication in eukaryotes. The present review summarizes current knowledge of how the core components of the archaeal chromosome replication apparatus interact with one another to perform their essential functions.
古菌染色体 DNA 复制装置的大多数核心组件与真核复制因子具有显著的蛋白质序列相似性，使古菌成为研究真核生物染色体复制生物学的极佳模型系统。本综述总结了目前关于古菌染色体复制装置的核心组件如何相互作用以发挥其基本功能的知识。
