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Laryngeal carcinoma metastasis to the orbit: case report.

作者信息

Galm T, Kulkarni A, Ahmad I

机构信息

Department of ENT, Heartlands Hospital, Birmingham, UK.

出版信息

J Laryngol Otol. 2011 May;125(5):533-5. doi: 10.1017/S0022215110002860. Epub 2011 Jan 27.

Abstract

OBJECTIVE

We present the first report in the all English literature of a case of laryngeal squamous cell carcinoma metastasis to the orbit.

METHOD

Case report of orbital metastasis from laryngeal carcinoma; clinical, radiological and pathological findings are discussed.

RESULT

A 75-year-old man presented to the ENT department with a five-week history of left orbital pain, swelling and reduced vision. Past medical history included laryngectomy, bilateral neck dissection and post-operative radiotherapy for T4 N2c M0 squamous cell carcinoma of the supraglottis, 10 months earlier. Imaging showed an orbital mass extending along the roof and lateral aspect of the orbit into the optic canal and superior orbital fissure, and further posteriorly into the left cavernous sinus with meningeal enhancement in the left anterior cranial fossa. Histopathological analysis after biopsy showed the mass to be consistent with metastatic poorly differentiated squamous cell carcinoma.

CONCLUSION

After searching the all English literature, we report what is, to our best knowledge, the first case of laryngeal carcinoma metastasis to the orbit. Despite its rarity and poor prognosis, such a metastasis should be considered as part of the differential diagnosis of an orbital mass, as timely recognition can improve the patient's quality of life.

摘要

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