利托那韦诱导的急性肾损伤：肾活检结果及文献综述
Ritonavir-induced acute kidney injury: kidney biopsy findings and review of literature.
作者信息
Shafi T, Choi M J, Racusen L C, Spacek L A, Berry C, Atta M, Fine D M
机构信息
Department of Medicine, Division of Nephrology, Johns Hopkins University School of Medicine, Baltimore, MD 21224-2780, USA.
出版信息
Clin Nephrol. 2011 Feb;75 Suppl 1(0 1):60-4. doi: 10.5414/cn106469.
Abstract
Ritonavir therapy is not generally considered nephrotoxic. We report a case of acute kidney injury secondary to ritonavir, with kidney biopsy demonstrating extensive acute tubular injury. This is the first report of a kidney biopsy and pathology in acute kidney injury associated with ritonavir. A review of published medical literature on the topic is also presented.
摘要
利托那韦疗法一般不被认为具有肾毒性。我们报告了一例继发于利托那韦的急性肾损伤病例，肾脏活检显示广泛的急性肾小管损伤。这是首例关于利托那韦相关急性肾损伤的肾脏活检及病理报告。本文还对该主题已发表的医学文献进行了综述。
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