Department of Geriatric Medicine, Medicine Division, Internal, Norwegian Centre for Dementia Research, Ullevaal University Hospital, Oslo, Norway.
Aging Ment Health. 2011 Apr;15(3):299-306. doi: 10.1080/13607861003713224.
To investigate the quality of life (QoL) and depression and its correlates in carers living with early onset dementia (EOD) patients.
The subjects were 49 carers, either married to or cohabiting with EOD patients, 38 with Alzheimer's disease and 11 with other types of dementia. The Quality of Life - Alzheimer Disease scale (QoL-AD) and Geriatric Depression Scale-15 items (GDS-15) were used.
The mean QoL score for the carers was 37.9 (SD 5.5) and the mean GDS-15 score 5.1 (SD 2.9). Linear regression analyses with QoL and GDS-15 score as dependent variables were performed. Increased age of the carer (B = 0.32) and greater insight of the patients (B = -0.186) were significantly associated with a better QoL for the carer. Being married (B = 2.10), having children together with the patient (B = 1.61) and being the carer of a patient with cardiovascular disease (B = 2.28) were associated significantly with a higher GDS-15 score, whereas being the carer of a patient who received domiciliary nursing care (B = -2.29) was significantly associated with a lower GDS-15 score.
The QoL for carers of EOD patients corresponds positively with the increased age of carers and with patients' insight into their condition. Increased depressive symptomatology in carers was associated with being married, having offspring and caring for a patient with dementia and a co-morbid cardiovascular disease. A reduction in depression was seen in carers when the patients received domiciliary nursing care.
调查与早期发病痴呆症(EOD)患者共同生活的照顾者的生活质量(QoL)和抑郁及其相关因素。
研究对象为 49 名照顾者,他们与 EOD 患者是已婚或同居关系,其中 38 名为阿尔茨海默病患者,11 名为其他类型痴呆症患者。采用生活质量 - 阿尔茨海默病量表(QoL-AD)和老年抑郁量表 15 项(GDS-15)进行评估。
照顾者的平均 QoL 得分为 37.9(SD 5.5),GDS-15 平均得分为 5.1(SD 2.9)。以 QoL 和 GDS-15 得分作为因变量进行线性回归分析。照顾者年龄的增加(B = 0.32)和患者认知能力的提高(B = -0.186)与照顾者的 QoL 呈显著正相关。与患者结婚(B = 2.10)、与患者育有子女(B = 1.61)以及照顾患有心血管疾病的患者(B = 2.28)与 GDS-15 得分较高显著相关,而照顾接受家庭护理的患者(B = -2.29)与 GDS-15 得分较低显著相关。
EOD 患者照顾者的 QoL 与照顾者年龄的增加和患者对自身状况的认知呈正相关。照顾者抑郁症状加重与已婚、育有子女、照顾患有痴呆症和合并心血管疾病的患者有关。当患者接受家庭护理时,照顾者的抑郁情绪会减轻。