Department of Neurobiology and Behavior, W245 Mudd Hall, Cornell University, Ithaca, NY 14853, USA.
J Neurophysiol. 2011 Apr;105(4):1432-43. doi: 10.1152/jn.00960.2010. Epub 2011 Jan 27.
The mammalian main olfactory bulb receives a significant noradrenergic input from the locus coeruleus. Norepinephrine (NE) is involved in acquisition of conditioned odor preferences in neonatal animals, in some species-specific odor-dependent behaviors, and in adult odor perception. We provide a detailed review of the functional role of NE in adult rodent main olfactory bulb function. We include cellular, synaptic, network, and behavioral data and use computational simulations to tie these different types of data together.
哺乳动物的嗅球主要从蓝斑接收大量的去甲肾上腺素能输入。去甲肾上腺素(NE)参与了新生动物条件性气味偏好的获得、某些特定于物种的气味依赖行为以及成年气味感知。我们提供了一个详细的综述,介绍了 NE 在成年啮齿动物嗅球功能中的功能作用。我们包括细胞、突触、网络和行为数据,并使用计算模拟将这些不同类型的数据联系起来。