Department of Pathology, Microbiology, Immunology, School of Veterinary Medicine, University of California, Davis, 4206 Vet Med 3A, Davis, CA 95618, USA.
Vet Pathol. 2011 Nov;48(6):1161-4. doi: 10.1177/0300985810396514. Epub 2011 Jan 27.
An 8-year-old male Nubian goat was presented with a peracute history of straining to urinate and unilateral mandibular swelling. At necropsy, the rostral half body of the left mandible was distorted by fusiform swelling that, on sagittal section, had marked medullary bone loss and replacement with a well-demarcated fibrous mass. Histologically, the mass comprised streaming spindloid cells with whorls and storiform patterns, interspersed with numerous multinucleated giant cells. Bone formation was not present in the neoplasm. The mandibular mass was diagnosed as nonossifying fibroma, a relatively common tumor in children but seldom reported in domestic animals.
一只 8 岁雄性努比亚山羊出现了排尿困难和单侧下颌肿胀的急性病史。剖检时,左侧下颌骨的前半部分被梭形肿胀所扭曲,矢状切片显示明显的骨髓骨丢失,并被一个界限清楚的纤维肿块所取代。组织学上,该肿块由漩涡状和棋盘状的流状纺锤形细胞组成,其间散布着大量多核巨细胞。肿瘤中没有骨形成。下颌肿块被诊断为非骨化性纤维瘤,这是儿童中相对常见的肿瘤,但在宠物中很少报道。