Departments of Surgical and Diagnostic Sciences, College of Dentistry, Dar Al Uloom University, Riyadh, Saudi Arabia.
Department of OMFS and Diagnostic Sciences, College of Dentistry, King Faisal University, Al Hufuf, Saudi Arabia.
Int J Mycobacteriol. 2023 Apr-Jun;12(2):196-206. doi: 10.4103/ijmy.ijmy_53_23.
Nonossifying fibroma (NOF) is a benign lesion confined to the bone marrow and connective tissues without exhibiting osseous metaplasia. NOF of long bones in children is more common than its gnathic counterpart. Mandibular NOF is rare, and there is a paucity of information in the literature. NOF of the jaws clinically presents as a nodular, fibrous, asymptomatic, gingival, or alveolar mucosal enlargement, with or without facial swelling. NOF differs from the ossifying type by the presence of metastatic woven bone in ossifying type. This article reports an example of bilateral, multilocular, NOF of the mandible in a 15-year-old female patient with unilateral, asymptomatic facial asymmetry. The radiographic features were characteristic of NOF. It was treated successfully with surgical excision and curettage. A 2-year postoperative follow-up showed recurrence of the right lesion and needed secondary surgical intervention, and the tumor on the left side, however, healed well without recurrence.
非骨化性纤维瘤(NOF)是一种局限于骨髓和结缔组织的良性病变,无骨改建。儿童长骨的 NOF 比颌骨更为常见。颌骨的 NOF 较为罕见,文献中相关信息较少。颌骨的 NOF 临床上表现为结节状、纤维状、无症状的牙龈或牙槽黏膜增大,伴或不伴面部肿胀。NOF 与骨化型的区别在于骨化型存在转移性编织骨。本文报道了一例 15 岁女性患者双侧、多房性下颌骨 NOF,伴单侧、无症状的面部不对称。影像学特征具有特征性。手术切除和刮除治疗效果良好。2 年的术后随访显示右侧病变复发,需要二次手术干预,而左侧病变愈合良好,无复发。