School of Optometry and Vision Science, University of New South Wales, Sydney, NSW, Australia.
Invest Ophthalmol Vis Sci. 2011 May 2;52(6):2911-6. doi: 10.1167/iovs.10-6763.
To examine the interrelationships among the Ocular Response Analyzer (ORA; Reichert Ophthalmic Instruments, Buffalo, NY), Goldmann applanation tonometer (GAT), and corneal geometry measurements in a young, healthy sample.
Central corneal radius, ORA, GAT, and central corneal thickness (CCT) measurements were taken in 99 subjects (age, 21 ± 2 years) who were free of ocular and systemic disease.
The mean ± SD corneal hysteresis (CH) and corneal resistance factor (CRF) were 10.4 ± 1.2 and 10.1 ± 1.5 mm Hg, respectively. The Bland-Altman 95% limits of agreement of ORA Goldmann-correlated IOP (ORAg) and ORA corneal-compensated (ORAcc) IOP with reference to GAT were -4.5 to +6.0 and -4.1 to +6.8 mm Hg, respectively. The full equations used by the ORA to calculate ORAcc and CRF were reconstructed. The statistically significant effect of CCT on GAT became redundant if CRF was included in a multivariate regression analysis. Both CH and CRF were associated with CCT (R(2) = 0.252 and 0.290, respectively).
Sample CH and CRF were consistent with those reported in the literature. ORAg and ORAcc agreed poorly with GAT. CRF appears to be at least a partial description of corneal rigidity. The ocular determinants of CH are unclear.
研究在年轻健康人群中，眼反应分析仪（ORA；Reichert 眼科仪器公司，纽约州布法罗）、Goldmann 压平眼压计（GAT）和角膜几何测量值之间的相互关系。
对 99 名（年龄 21±2 岁）无眼部和系统性疾病的受试者进行中央角膜半径、ORA、GAT 和中央角膜厚度（CCT）测量。
平均角膜滞后（CH）和角膜阻力因子（CRF）分别为 10.4±1.2mmHg 和 10.1±1.5mmHg。ORA 与 GAT 相关的 Goldmann 眼压（ORAg）和 ORA 角膜补偿（ORAcc）IOP 的 Bland-Altman 95%一致性界限分别为-4.5 至+6.0mmHg 和-4.1 至+6.8mmHg。重建了 ORA 计算 ORAcc 和 CRF 所使用的完整方程。如果将 CRF 纳入多元回归分析，GAT 对 CCT 的统计学显著影响变得多余。CH 和 CRF 均与 CCT 相关（R²分别为 0.252 和 0.290）。
样本 CH 和 CRF 与文献报道的一致。ORAg 和 ORAcc 与 GAT 一致性差。CRF 似乎至少部分描述了角膜刚性。CH 的眼部决定因素尚不清楚。
