Grieco T, Rossi M, Faina V, De Marco I, Pigatto P, Calvieri S
Department of Dermatology, Universitá di Roma "La Sapienza", Viale del Policlinico, 155, 00161 Rome, Italy.
J Allergy (Cairo). 2011;2011:752098. doi: 10.1155/2011/752098. Epub 2011 Jan 11.
Rivastigmine is a cholinesterase inhibitor which improves cognitive function and is currently being used in patients with mild to moderate Parkinson's and Alzheimer's dementia. This drug can be given orally or topically, as transdermal patch. The latter form is currently used for most excellent compliance and few side effects. The most common cutaneous side effects are irritative dermatitis. We report the second case of active sensitization by the rivastigmine-patch in a patient suffering from Alzheimer's dementia.
卡巴拉汀是一种胆碱酯酶抑制剂，可改善认知功能，目前用于治疗轻至中度帕金森病和阿尔茨海默病性痴呆患者。这种药物可以口服或局部给药，如透皮贴剂。后一种剂型目前因其极佳的顺应性和较少的副作用而被广泛使用。最常见的皮肤副作用是刺激性皮炎。我们报告了第二例患有阿尔茨海默病性痴呆的患者因卡巴拉汀贴剂发生主动致敏的病例。
