Quality, Audit and Risk Management Team, HSE-Dublin Mid Leinster, Midlands Regional Hospital Mullingar, Mullingar, Westhmeath, Ireland.
Ir J Med Sci. 2011 Jun;180(2):457-61. doi: 10.1007/s11845-011-0677-5. Epub 2011 Jan 28.
Point prevalence surveys (PPS) are increasingly used to examining and compare hospital antibiotic consumption. The aim of this study was to identify the (1) point prevalence of antibiotic use in one regional hospital and (2) compare PPS data from similar regional/general hospitals.
Data were collected on all inpatients with an active antibiotic prescription and on all prescriptions issued in the emergency department over a 24-h period. Point prevalence data were obtained from three other regional/general hospitals.
The frequency of antibiotic use was hospital A = 29%, B = 38%, C = 34% and D = 37%. Overall, the most commonly prescribed antibiotic was co-amoxiclav (30%), followed by macrolides (12%). However, new generation broad-spectrum antibiotics, such as piperacillin/tazobactam or ciprofloxacin, were also commonly used. Prescribing for common conditions such as respiratory infection or cellulites showed diverse antibiotic selection.
Point prevalence survey data using a standardised methodology could facilitate both local audit and national benchmarking to monitor antibiotic use.
目前越来越多地采用时点患病率调查（PPS）来检测和比较医院抗生素的使用情况。本研究旨在确定：（1）一家区域性医院的抗生素使用时点患病率；（2）比较来自类似区域性/综合性医院的 PPS 数据。
在 24 小时内收集所有使用抗生素的住院患者和急诊科所有开具的处方的数据。时点患病率数据来自另外三家区域性/综合性医院。
抗生素使用率分别为：医院 A = 29%、B = 38%、C = 34%和 D = 37%。总体而言，最常开的抗生素是复方阿莫西林（30%），其次是大环内酯类（12%）。然而，也经常使用新的广谱抗生素，如哌拉西林/他唑巴坦或环丙沙星。针对常见疾病（如呼吸道感染或蜂窝织炎）的处方显示出抗生素选择的多样性。
使用标准化方法的时点患病率调查数据可便于进行本地审核和国家基准测试，以监测抗生素的使用情况。
