David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA.
Dermatol Ther. 2011 Jan-Feb;24(1):2-27. doi: 10.1111/j.1529-8019.2010.01375.x.
The purpose of this article is to discuss current techniques used with poly-l-lactic acid to safely and effectively address changes observed in the aging face. Several important points deserve mention. First, this unique agent is not a filler but a stimulator of the host's own collagen, which then acts to volumize tissue in a gradual, progressive, and predictable manner. The technical differences between the use of biostimulatory agents and replacement fillers are simple and straightforward, but are critically important to the safe and successful use of these products and will be reviewed in detail. Second, in addition to gains in technical insights that have improved our understanding of how to use the product to best advantage, where to use the product to best advantage in facial filling has also improved with ever-evolving insights into the changes observed in the aging face. Finally, it is important to recognize that a patient's final outcome, and the amount of product and work it will take to get there, is a reflection of the quality of tissues with which they start. This is, of course, an issue of patient selection and not product selection.
本文旨在探讨目前使用聚左旋乳酸（poly-l-lactic acid）的技术，以安全有效地解决衰老面容中观察到的变化。有几个重要的问题值得一提。首先，这种独特的制剂不是填充物，而是宿主自身胶原蛋白的刺激物，然后以逐渐、渐进和可预测的方式使组织体积增大。生物刺激剂和替代填充物的使用之间的技术差异简单明了，但对这些产品的安全和成功使用至关重要，将详细审查。其次，除了在技术上的深入了解方面取得了进展，这些进展提高了我们对如何充分利用产品的理解外，在面部填充中充分利用产品的最佳位置也随着对衰老面容中观察到的变化的不断发展的认识而得到改善。最后，重要的是要认识到，患者的最终结果，以及达到该结果所需的产品数量和工作量，反映了他们开始时的组织质量。当然，这是一个患者选择的问题，而不是产品选择的问题。
