Alessio Redaelli, Rzany Berthold, Eve Linda, Grangier Yann, Herranz Pedro, Olivier-Masveyraud Frédérique, Vleggaar Danny
J Drugs Dermatol. 2014 Sep;13(9):1057-66.
Over the last few years, there have been a number of important changes in how we appreciate and understand the aging face. Volume loss is now recognized as a major component of facial aging. Treatment options that replace lost volume are increasingly used for recontouring and rejuvenation of the aging face. In this review we present and discuss the European Expert Group recommendations on the ideal use of the unique collagen stimulator, poly-L-lactic acid (PLLA, Sculptra®, Sinclair Pharmaceuticals) for facial rejuvenation lasting up to 25 months. Optimal results are achieved based on a detailed knowledge of facial anatomy, correct treatment procedure, specifically the right dilution, the correct injection technique, as well as appropriate patient aftercare. PLLA is an effective and safe collagen stimulator that treats the whole face. PLLA is simple to use, provides the foundation for facial rejuvenation, is easy to combine with other treatments, and gives long-lasting effects with a high level of patient satisfaction.
在过去几年里，我们对面部衰老的认识和理解发生了一些重要变化。现在人们认识到容量流失是面部衰老的一个主要因素。用于补充流失容量的治疗方法越来越多地被用于重塑衰老面部轮廓和实现面部年轻化。在本综述中，我们展示并讨论了欧洲专家组关于理想使用独特的胶原蛋白刺激剂聚左旋乳酸（PLLA，塑然雅®，辛克莱制药公司）进行长达25个月面部年轻化治疗的建议。基于对面部解剖结构的详细了解、正确的治疗程序，特别是合适的稀释度、正确的注射技术以及适当的患者术后护理，可取得最佳效果。PLLA是一种有效且安全的胶原蛋白刺激剂，可对面部整体进行治疗。PLLA使用简便，为面部年轻化奠定基础，易于与其他治疗方法结合，且效果持久，患者满意度高。
