Arthritis Research UK Primary Care Centre, Keele University, Newcastle-under-Lyme, Staffordshire, UK.
Br J Gen Pract. 2011 Feb;61(583):128-30. doi: 10.3399/bjgp11X556263.
Using a prescription-survey linkage dataset for 4506 people aged ≥50 years from six general practices, the null hypothesis that multiple drug prescribing was not associated with changes in health over a 3-year time-period was investigated. There was a significant trend in the adjusted association between higher levels of multidrug therapy and deterioration in both physical and psychological health over a 3-year time period. The study highlights the potential need for assessing drug prescribing in terms of overall health.
利用来自 6 家全科诊所的 4506 名年龄≥50 岁人群的处方调查数据集，研究了多药处方与 3 年时间内健康变化之间无关联的零假设。在 3 年时间内，多药治疗水平与身体和心理健康恶化之间的调整关联呈显著趋势。该研究强调了根据整体健康状况评估药物处方的潜在需求。
