Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC 27710, USA.
J Shoulder Elbow Surg. 2011 Mar;20(2):259-66. doi: 10.1016/j.jse.2010.10.037.
Management of a first-time anterior shoulder dislocation (FTASD) involves important clinical and policy decisions. Predictive disease modeling can improve the quality of information disseminated in treatment discussions. In this paper, we describe a general-purpose, publicly available model and illustrate its potential as a tool for management of a FTASD.
A Markov decision model of the natural history of a FTASD was constructed. Outcome probabilities and effectiveness were derived from the literature or estimated by expert opinion where necessary. Outcomes were the Western Ontario Shoulder Instability index (WOSI) and the probability of a patient experiencing recurrent instability, undergoing surgical stabilization, and having a stable shoulder at 10 years. The model was both internally and externally validated. Outcomes were examined for specific cases.
The model was effectively externally validated against two studies, a Swedish prospective cohort of Hovelius et al and Botonni et al's military cohort. It can produce detailed outcome predictions for individuals; eg, an 18-year-old man has a 77% risk of dislocation in year 1 and a 32% chance of having a stable shoulder in 10 years.
Detailed and specific information about prognosis is critical in the management of a FTASD. Disease modeling lends itself well to these needs and allows improved shared decision-making. Our model was externally validated and can predict specific outcomes. As a publically available resource, it will allow physicians to accurately predict the expected outcome of treatment based on covariates, patient demographics, and their own surgical success rates.
初次肩关节前脱位(FTASD)的治疗管理涉及重要的临床和政策决策。预测疾病模型可以提高治疗讨论中信息传播的质量。在本文中,我们描述了一种通用的、可公开获得的模型,并说明了其作为 FTASD 管理工具的潜力。
构建了 FTASD 自然史的马尔可夫决策模型。根据文献或必要时通过专家意见得出结果概率和有效性。结果是 Western Ontario 肩不稳定指数(WOSI)和患者经历复发性不稳定、接受手术稳定以及 10 年后肩部稳定的概率。该模型进行了内部和外部验证。对特定病例进行了结果检查。
该模型有效地与两项研究进行了外部验证,一项是 Hovelius 等人的瑞典前瞻性队列研究,另一项是 Botonni 等人的军事队列研究。它可以为个体产生详细的预后预测;例如,18 岁的男性在第 1 年脱位的风险为 77%,10 年后肩部稳定的机会为 32%。
在 FTASD 的治疗管理中,详细和具体的预后信息至关重要。疾病建模非常适合这些需求,并允许更好地进行共同决策。我们的模型经过外部验证,可以预测特定的结果。作为一个公共资源,它将使医生能够根据协变量、患者人口统计学特征和他们自己的手术成功率准确预测治疗的预期结果。