Department of Neurology, Charité Campus Virchow Klinikum, Augustenburger platz 1, 13353, Berlin, Germany.
Clin Auton Res. 2011 Jun;21(3):161-8. doi: 10.1007/s10286-010-0114-2. Epub 2011 Jan 30.
Although orthostatic dizziness (OD) is a common complaint, its prevalence and medical impact in the general population are unknown. The study aims to assess prevalence, medical sequelae and healthcare and social impact of OD in the general population. Participants of the representative German National Health Interview Survey 2003 (n = 4077, age 18-89 years, response rate 52%) were screened for moderate or severe dizziness or vertigo. As part of a larger study on the epidemiology of dizziness and vertigo, a consecutive subsample of screen-positive participants (n = 825) underwent a structured medical interview for OD based on the criteria: (1) non-vestibular dizziness (i.e. diffuse non-rotational dizziness, light headedness, feeling of impeding faint), (2) provocation by sudden postural change (i.e. standing up from supine or sitting), (3) duration of seconds to several minutes, (4) absence of vestibular vertigo according to a validated neurotologic interview. The 12-month prevalence of OD was 10.9% (women 13.1%, men 8.2%), lifetime prevalence was 12.5% (women 15.0%, men 9.6%). OD accounted for 42% of all participants with dizziness/vertigo and for 55% of non-vestibular dizziness diagnoses. The prevalence of OD was highest in young people, although the proportion with severe OD steadily increased with age. OD led to syncope in 19%, falls in 17% and traumatic injury in 5% of affected subjects. Almost half of the individuals with OD (45%) had consulted a physician and 4% had been treated in hospital. OD is a frequent cause of non-vestibular dizziness for which patients often seek medical advice. It carries a considerable risk of syncope, falls and traumatic injury.
虽然直立性头晕(OD)是一种常见的主诉,但它在普通人群中的流行程度和对健康的影响尚不清楚。本研究旨在评估普通人群中 OD 的患病率、医疗后果以及对医疗保健和社会的影响。
在具有代表性的德国 2003 年国家健康访谈调查中,对 4077 名年龄在 18-89 岁的参与者(应答率为 52%)进行了中度或重度头晕或眩晕的筛查。作为一项关于头晕和眩晕流行病学的更大研究的一部分,对屏幕阳性参与者的连续亚样本(n=825)进行了基于以下标准的 OD 结构化医学访谈:(1)非前庭性头晕(即弥漫性非旋转性头晕、头晕、有晕倒的感觉);(2)由突然的姿势变化引起(即从仰卧位或坐位站起);(3)持续数秒到数分钟;(4)根据经过验证的神经耳科访谈,无前庭性眩晕。OD 的 12 个月患病率为 10.9%(女性 13.1%,男性 8.2%),终身患病率为 12.5%(女性 15.0%,男性 9.6%)。OD 占所有头晕/眩晕患者的 42%,占非前庭性头晕诊断的 55%。OD 的患病率在年轻人中最高,尽管严重 OD 的比例随着年龄的增长而稳步增加。OD 导致 19%的受影响者晕厥,17%的受影响者跌倒,5%的受影响者遭受创伤性损伤。OD 患者中有近一半(45%)曾就诊于医生,4%曾住院治疗。OD 是一种常见的非前庭性头晕的病因,患者常因此寻求医疗建议。它有相当大的晕厥、跌倒和创伤性损伤的风险。