Suppr超能文献

致力于慢性硬膜下血肿的合理且基于证据的治疗。

Working toward rational and evidence-based treatment of chronic subdural hematoma.

作者信息

Santarius Thomas, Kirkpatrick Peter J, Kolias Angelos G, Hutchinson Peter J

机构信息

Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom.

出版信息

Clin Neurosurg. 2010;57:112-22.

Abstract

Chronic subdural hematoma (CSDH) is one of the most common neurosurgical conditions that can usually be treated with relatively simple and effective surgical procedures. It affects primarily the elderly, a rising population worldwide. Together with improved awareness among the medical profession and greater access to modern imaging facilities, the incidence of CSDH is set to rise significantly. Maximization of the efficiency of management of CSDH is therefore a priority. To this end, a review of the findings of clinical and laboratory research underpinning the basis of the modern management of CSDH has been carried out. This review focuses on the pathophysiology and briefly discusses the epidemiology, clinical presentation, and surgical treatments of CSDH, concluding that a one-for-all management strategy is not appropriate. Creating rational bases for the selection of an ideal treatment strategy for an individual patient should be the target. This can be achieved through better understanding of the nature of the condition through systematic basic science research, ascertaining the merits of different surgical techniques in well-designed and rigorously executed clinical trials, using advances in imaging techniques to classify CSDH (a subject not addressed here), and training in and ongoing refinement of clinical acumen and surgical skills of individual surgeons.

摘要

慢性硬膜下血肿(CSDH)是最常见的神经外科疾病之一,通常可通过相对简单有效的手术方法进行治疗。它主要影响老年人,而全球老年人口正在增加。随着医学界认识的提高以及现代影像设备的更广泛使用,CSDH的发病率预计将显著上升。因此,提高CSDH的管理效率是当务之急。为此,我们对支持CSDH现代管理基础的临床和实验室研究结果进行了综述。本综述重点关注病理生理学,并简要讨论CSDH的流行病学、临床表现和外科治疗,得出“一刀切”的管理策略并不合适的结论。为个体患者选择理想治疗策略建立合理依据应是目标。这可以通过系统的基础科学研究更好地了解病情本质、在设计良好且严格执行的临床试验中确定不同手术技术的优点、利用影像技术进展对CSDH进行分类(本文未涉及该主题)以及对个体外科医生的临床敏锐度和手术技能进行培训并不断完善来实现。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验