Talbot K, Simpson R, Price N, Jackson S R
The John Radcliffe Hospital, Oxford, UK.
J Obstet Gynaecol. 2011;31(1):7-12. doi: 10.3109/01443615.2010.522749.
Heterotopic pregnancy is a life-threatening condition. A recent case at our institution prompted a systematic review of the literature from 2005 to 2010. In the majority (71%) of cases reviewed, risk factors for a heterotopic pregnancy were present. However, in several instances (33%), previous sonographic reports of a normal intrauterine pregnancy gave false reassurance. These results highlight the complexity of diagnosis. In addition, our findings were compared with two previous reviews covering cases from 1971 to 2004. This comparison highlighted two important trends: first, the increasing role of ultrasound in the definitive diagnosis of a heterotopic pregnancy, and second, the development of conservative approaches to management. Medical knowledge and technology may be improving, but ultimately, even in the presence of a known intrauterine pregnancy, the simple dictum 'think ectopic' must not be forgotten.
异位妊娠是一种危及生命的情况。我们机构最近的一个病例促使对2005年至2010年的文献进行了系统回顾。在大多数（71%）回顾的病例中，存在异位妊娠的风险因素。然而，在一些病例（33%）中，先前关于宫内妊娠正常的超声报告给出了错误的安心结论。这些结果凸显了诊断的复杂性。此外，我们的研究结果与之前两篇涵盖1971年至2004年病例的综述进行了比较。这种比较凸显了两个重要趋势：第一，超声在异位妊娠明确诊断中的作用日益增加；第二，保守治疗方法的发展。医学知识和技术可能在进步，但最终，即使存在已知的宫内妊娠，“想到异位妊娠”这条简单的原则也绝不能被遗忘。
